Founded in 1961, the Antoine Lacassagne Center is a Private Health Establishment with public service mission. As a French Comprehensive Cancer Center, member of the Unicancer network, it carries out care, research and hospital-university teaching missions in oncology.

Each year, more than 6,000 patients are taken care of by the establishment. From screening to follow-up after treatment.

In 2022, the establishment is ranked among the 100 best cancer hospitals in the world (Newsweek 2022 ranking) and 9th nationally. It is recognized as a regional, national and international center of reference for oncology.

With all the radiotherapy treatment techniques, it has one of the most complete technical platforms in Europe. An expert referral center in complex cervico-facial oncological surgery, the Antoine Lacassagne Center is also a leader in its health territory in the management of breast and gynecological cancers.


Key figures for 2021: 197 beds and places, 863 employees, 6,280 patients treated, 547 patients included in clinical trials, nearly 64,000 medical consultations, more than 60,000 hospital stays.

>> Find out more:


Department of Radiotherapy of the Antoine Lacassagne Cencer Center


A state-of-the-art technical platform for personalised medicine


The Antoine Lacassagne Cancer Center is one of the only facilities in France to have all the irradiation treatment techniques, ranging from contact radiotherapy (50 kV) to low- and high-energy proton therapy, including brachytherapy, robotic (Cyberknife®) stereotaxic radiotherapy (cranial and extra-cranial), helical radiotherapy (Tomotherapy) and intensity modulated radiotherapy (IMRT), image-guided with dynamic arc therapy. 


Department of Radiotherapy: Key figures 2022

2,232 different patients treated

2,694 preparation sessions

28,566 irradiation sessions

1,725 in-patient irradiation procedures


The Antoine Lacassagne Centre's Radiotherapy Centre is located on two sites:


  • The East site 

Address: 33 avenue de Valombrose, Nice, 

Contact: +33 (0) 4 92 03 10 00


  • IMPT - Mediterranean Institute of ProtonTherapy CyberKnife® (West site)

Address: 227 avenue de la Lanterne, Nice,

Contact: +33 (0) 4 92 03 10 84


Innovative treatments offered on the East site



Contact radiotherapy: 


Contact radiotherapy is a low-energy photon irradiation technique for cancers of the rectum and breast.



With the Papillon 50 and Papillon+ devices, the Antoine Lacassagne Centre is able to offer contact radiotherapy to treat:

  • Adenocarcinoma of the rectum 
  • Some cutaneous tumours particularly peri-orificial (eyelid, tip of the nose, etc.).
  • Small-sized breast cancers in some patients over 60 years using intra operative approach





At the Antoine Lacassagne Centre, a "high dose rate" brachytherapy technique is proposed.



  • Prostate cancer in addition to external radiotherapy
  • Breast cancer
    • As the first-line treatment for a partial irradiation of the breast: 2 to 3 days instead of 5 to 6 weeks.
    • In case of a local relapse: a second conservative treatment instead of mastectomy.
  •  Cervical cancer after concomitant radiochemotherapy: therapeutic standard. 



The Mediterranean Institute of Proton Therapy - CyberKnife®


Cyberknife®Accélérateur linéaire sur le bras robotisé

CyberKnife® delivers stereotaxic radiotherapy (very precise) for curative and conservative purposes in several areas, particularly in fragile patients and for mobile tumours.



Stage I or II lung cancer, isolated pulmonary metastasis, primary liver cancer, isolated hepatic metastasis, isolated cerebral metastasis 





What is protontherapy?

Proton therapy is radiation therapy using proton beams.


Thanks to the proton stopping characteristics in tissues : it delivers a virtually zero dose beyond the target.













As early as 1991, the Antoine Lacassagne Centre acquired the 1st  low energy (63 MeV) proton therapy device in France


Medicyc, the first low-energy proton therapy device, has been specifically designed and calibrated for the treatment of melanoma of the eye.  This configuration is unique in the world.  A single treatment of 4 proton sessions is sufficient, to cure patients in more than 70% of cases.

To date, the Centre has treated more than 5,500 patients from around the world and has world-renowned expertise validated by numerous publications.


Since 2016, the Centre has expanded its proton therapy solution with Proteus® One (IBA), the world's first new generation of high-energy proton (230 MeV) therapy equipment. 


In addition to the intrinsic ballistic qualities of beams from a proton therapy system, this new prototype incorporates a unique irradiation technique developed in Nice using Pencil Beam Scanning (PBS), which allows the development of simpler and more precise treatment plans with a dose distribution that perfectly matches the volume of the irradiated tumour.



  • Ocular tumours
  • Tumours difficult to access or close to organs at risk (chordomas and chondrosarcomas, para-spinal tumours, tumours of the base of the skull, sinus tumours)
  • All paediatric tumours.  This high precision system for the treatment of tumours in children avoids irradiating neighbouring healthy tissues and prevents the occurrence of radiation-induced cancers whose likelihood increases sharply in children




To learn more about the Mediterranean Institute of ProtonTherapy



"La Consolata", patient accommodation structure


For greater access to treatment, the Antoine Lacassagne Centre has designed a unique model with its own accommodation structure, "La Consolata", to accommodate patients and their companions from around the world.

The patient benefits from comprehensive and personalised care where all the stages of the treatment are organised: transport, accommodation, treatment organisation, relations with the attending physician, possibility of interpreting, etc.

La Consolata is located on the heights of Nice, a few minutes from the Mediterranean Institute of Proton Therapy, in a calm and relaxing environment with a panoramic view of the Baie des Anges.


In 2018, the Regional Health Agency PACA certified La Consolata in its regional directory of patient accommodation structures.  This certification is a real recognition of the activity carried out in the Antoine  Lacassagne Centre's patient accommodation structure.

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